The region is home to a diverse set of major industries and a broad-based network of ancillary and supporting businesses. The list below highlights our top major employers in the area: manufacturing, service, support, transportation, office, professional industries.
| 4,000 | Archer Daniels Midland |
| 3150 | Caterpillar |
| 1903 | Decatur Memorial Hospital |
| 1,752 | Decatur Public Schools |
| 930 | HSHS St. Mary’s Hospital |
| 600 | Millikin University |
| 575 | The Kelly Group |
| 600 | Akorn Incorporated |
| 600 | Primient |
| 630 | Ameren Illinois |
| 380 | Norfolk Southern |
| 585 | Mueller |
| 400 | Bodine Electric |
| 300 | A-Lert Construction Services |
| 250 | McLeod Express |
| 175 | Fuyao Glass |
| 150 | TCR Systems |
| 125 | T/CCI Manufacturing |
| 80 | Parke Warehouses |