The region is home to a diverse set of major industries and a broad-based network of ancillary and supporting businesses. The list below highlights our top major employers in the area: manufacturing, service, support, transport, office, professional industries.
| 4,000 | Archer Daniels Midland |
| 3,100 | Caterpillar |
| 2,300 | Decatur Memorial Hospital |
| 1,800 | Decatur Public Schools |
| 900 | St. Mary’s Hospital |
| 650 | Ameren |
| 600 | Tate & Lyle |
| 500 | Akorn |
| 500 | Mueller |
| 500 | Macon County |
| 500 | City of Decatur |